I have a 3RZ, not a 22RE...
Fuel Cell = RCI Rock Crawler 2161J 15 gallon cell with bladder. I made a custom mount for it in my buggy.
Pump/Filters = Walbro GSL391 Inline Fuel Pump 190LPH. Kit came with 2 inline fuel filters (1 pre and 1 post). I used the pre-pump filter from the kit, and left my factory post-pump filter in place.
Fittings/Lines = I used AN-to-barb fittings at the fuel cell. I ran regular rubber EFI fuel hose and hose clamps to the pre-pump filter, then to the pump, then to the factory post-pump filter. My return is also regular rubber EFI fuel hose and hose clamps all the way back to the cell, which again has AN-to-barb fitting.
https://www.summitracing.com/parts/SUM-220766B
@pitbullcruiser's setup is very nice, and having all AN/threaded fittings is good.
I have had no issues or leaks out of my setup.