From what I've gathered, one of the biggest issues with the 6 speeds was the torque converter/torque converter clutch. I've seen stock (internals) do much better and live longer with a good, aftermarket converter and some tuning.
I'm not sold on GM's use of the 10 speed just yet. Ford "seems" to have it figured out a little better with aforementioned differences in software, tcm tuning, and (unbeknownst to me) some different internal parts/materials.
I do know of two guys that had '20/'22 model (1500) trucks bought back for constant transmission issues that dealerships tried to pass off as faulty injectors. Even the 10 speed "Allison" 10L1000 seems to have its share of faults.
Oh, one guy at work said his wife's transmission just crapped out. 2018 Chevy ½ ton. Said the temperature started creeping up. The "shop" told him it was a pump issue, which I don't believe. I haven't driven it, but I'm betting it's a converter issue. He said it shifts fine, but starts getting hotter the longer you drive it at highway speeds. Likely because the converter clutch came apart, partially blocked the cooler inlet passage, and since the converter can't lock, it just makes more and more heat.
It's a bit ridiculous what they charge for a stock rebuild/replacement on a 6 speed. I think he said 4200 bucks? Shoot...I'd absolutely throw some aftermarket parts in and do it myself for that kinda money!
All of this is a moot point for me, personally. I have no intentions of buying anything else or newer than what I've got. Just sharing some experiences from guys I work with.